I wanted to love nixos but it has many shortcomings that aren’t immediately obvious but can really stump you. No FHS compatibility seems fine but certain programs require it and don’t have nix native workarounds. Additionally, the documentation is really not good. I used it for a while but it got in the way too much; now I use a fedora variant and use regular Nix for dev packages using nix-direnv. Gives me the nix features while also having a fully compliant and functional base system
Well there are compatibility layers but they aren’t perfect. I’ve tried nix-ld, nix-alien, and nix-autobahn and each does work but not necessarily in all cases. I found this to be most common with scripts.
For example, I tried to install the discord mod Vencord using these solutions, but even with the compatibility shell I could not get past the first prompt.
Another issue I had was network authentication. An organization I’m in has a secure network requiring a web portal to sign in, and it uses a python script to get hardware details and install a certificate. This does not work even with FHS compatibility layers. I manually installed all of the python packages it wanted, which got it to launch and immediately crash. On traditional distros, it just works
I’m rambling but yes these tools exist and they may make everything rosy for you, but be aware of their own limitations because they didn’t solve much for me